Research Interests

My research activity has been motivated mainly by real problems and novel experiments when analyzing high-throughput data using statistical and computational methods and collaborating on scientific or industrial research projects.
My past experience spans a wide range of statistical and computational methods, including Wavalets and Denoising, non-parametric regression, functional data analysis, multiple hypothesis testing, and clustering. I have demonstrated my versatility by applying frequentist and Bayesian approaches to these problems.
More recently, my interest has focused on analyzing high-dimensional data problems arising from genomics, biology, and medicine. I have worked on various problems in statistical genomics, including methods for analyzing time-course microarray gene expression data, identifying transcription factor binding sites using variable selection approaches, and analyzing Next Generation Sequencing Data. Current research activity includes applications to Epigenomics and Transcriptomics with great interest in single-cell technologies, High dimensional data analysis, data integration, and Network analysis using graphical models. Moreover, I am interested in developing efficient software for analyzing a wide range of omics data and user-friendly tools.
Since January 2012, I have led the Laboratory of Statistics and Computational tools for Bioinformatics (BioinfoLab).

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Ongoing Research Projects.

Past Research Projects.

MEDIA (2020-2022)

Metodiche diagnostiche ad alta efficienza per il paziente osteo-articolare: MRI dedicata per imaging non invasivo pre- e post operatorio nell'impianto di protesi e sistemi integrati di ausilio alla gestione del dato clinico/diagnostico.

ADViSE (2019-2022)

Piattaforma tecnologica per la lotta alle patologie oncologiche
Regione Campania.

INCIPIT (2015-2020)

HORIZON 2020/Marie Sklodowska Curie Action: INnovative Life sCIence Phd Programme in South Italy — INCIPIT

BioforIU (2012-2015)

PONa3_00025: BIOforIU Infrastruttura multidisciplinare per lo studio e la valorizzazione della Biodiversita marina e terrestre nella prospettiva della Innovation Union.

Diagen-sc (2012-2015)

PON01_02460: Studio per la realizzazione di un presidio diagnostico per l'individuazione di strategie terapeutiche personalizzate per il diabete di tipo 2 mediante approcci di genomica e trascrittomica.

RSTL (2008-2010)

CNR-RSTL n.26: Metodi Bayesiani di selezione delle variabili con applicazioni alla genomica.

Regressione non-parametrica e wavelets (2001)

Progetto Giovani ricercatori Università degli Studi di Napoli