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TFF1

trefoil factor 1

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.


  Gene Expression Pattern     Gene Network    dbSNP    OMIM  


TRANSCRIPTS LIST

5'/3'UTRs Partially Coding Exons Coding Exons Introns



Promoter 3'UTR

NM_003225; ENST00000291527.2

Gene: NM:NM_003225; ENST00000291527.2 EXON 1 EXON 1 EXON 2 EXON 2 EXON 3 EXON 3 INTRON 1 INTRON 2





Updated on June 12, 2013