Who we are ...
ALE-HSA21 has been developed merging the biological background of the of the Human Genetics Disease Laboratory at IGB
IGB lead by Prof. Ciccodicola
Alfredo and coordinated by Dr. Costa Valerio, with the computational competency of the IAC group coordinated by Dr. Angelini Claudia.
Since 2007, the IGB team
has been studying, from a genetic perspective, the trisomy of chromosome 21, the genetic cause of Down syndrome. Both research groups tightly
collaborate to data analysis of RNA-Seq experiments (whole transcriptome), performed by the
Next Generation Sequencing (NGS).
The IAC team is expert in developing highly advanced mathematical, statistical and computational methods
to solve problems having a high impact on applications in a mainly multidisciplinary framework and also
in software, database and website implementation.
Both research teams are actively participating to the CNR
Interomics Flagship Project and are MC members of the COST-Action:
“Next Generation Sequencing Data Analysis Network” connecting researchers working in the field of NGS at a European level.
The research group
"Human Genetic Disease Laboratory" at Institute of Genetics and Biophysics "A. Buzzati-Traverso" (IGB), CNR, Naples, Italy
| Ambrosio Maria Rosaria | PhD student in Oncology and Molecular Endocrinology University of Naples “FEDERICO II”, Naples, Italy |
mariarosaria.ambrosio@igb.cnr.it |
| Aprile Marianna | PhD student in Cellular and Molecular Biotechnology "Second University of Naples" (SUN), Naples, Italy |
marianna.aprile@igb.cnr.it |
| Aversa Rosanna | PhD student in Cellular and Molecular Biotechnology "Second University of Naples" (SUN), Naples, Italy |
rosanna.aversa@igb.cnr.it |
| Ciccodicola Alfredo | Principal Investigator of the InterOmics IGB Unit and Professor of Genetics at the University of Naples "Parthenope", Naples, Italy | alfredo.ciccodicola@igb.cnr.it |
| Costa Valerio | PostDoc at IGB-CNR and Teaching Assistant at the University of Naples "Parthenope", Naples, Italy | valerio.costa@igb.cnr.it |
| Esposito Roberta | PhD Student in System Biology University of Salerno "Hyppocratica Civitas", Salerno, Italy |
roberta.esposito@igb.cnr.it |
| Scarpato Margherita | PhD student in Advanced Biology University of Naples “FEDERICO II”, Naples, Italy |
margherita.scarpato@igb.cnr.it |
"Laboratory of Statistics & Bioinformatics" at Istituto per le Applicazioni del Calcolo "Mauro Picone" (IAC),CNR, Naples, Italy
| Angelini Claudia | Principal Investigator of the InterOmics IAC Unit | c.angelini@iac.cnr.it |
| Evangelista Daniela | PhD student in Computational Biology "Second University of Naples" (SUN), Naples, Italy |
d.evangelista@na.iac.cnr.it |