ALE-HSA21

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and is clustered with CLDN8 on chromosome 21q22.11. [provided by RefSeq, Jun 2010]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

  Gene Expression Pattern     Gene Network    dbSNP    OMIM  

TRANSCRIPTS LIST

5'/3'UTRs Partially Coding Exons Coding Exons Introns

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Promoter 3'UTR

NM_012131; ENST00000286808.3